Course

Unit 1: Medicinal agents from natural products (10 Hrs)History of the use of natural products as therapeutic agents, medicinal plants, active principle, isolation methods of alkaloids and terpenes, antioxidants, natural oils from plants.Unit 2: Classes of Medicinal Agents I (10 Hrs)Medicinal agents belonging to alkaloids, steroids, polypeptides, modified nucleic acid bases, sulphonamide and sulpha drugs, antibacterials – sulpha drugs, substituted sulphonamides.Unit 3 Classes of Medicinal Agents II (10 Hrs)Anticonvulsants, anticoagulants, antiamoebic agents, antihelmintic agents, anti-malarial agents, diuretics and cardiovascular agents.Unit 4: Medicinal agents affecting CNS (10 Hrs)Medicinal agents affecting CNS: analgesics, antipyretics, antiseptics and disinfectants, histamine and anti-histaminic agents.Unit 5: Infectious and non-infectious diseases (8 Hrs)Infectious and non-infectious diseases (malaria, AIDS, cancer) – introduction, mechanism of action, types of cures.

1. Course OverviewPharmacotherapeutic Compounds is a course offered to 4-year B.Sc. (Honours) with/without Research and 5-year Integrated M.Sc. students in the department of chemistry. This course is curated to introduce various types of medicinal agents used to treat different diseases. 2. Course OutcomeCO1: To explore medicinal agents derived from natural productsCO2: To examine the various classes of medicinal agentsCO3: To examine the causes and effects of infectious and non-infectious diseases

References:1. A. Burger, Medicinal Chemistry, 3rd edition, Wiley Interscience, 1970.2. V. K. Ahluwalia and Madhu Chopra, Medicinal Chemistry, Ane Books pvt Ltd, 2008.3. V. Kothekar, Essentials of Drug Designing, 14th edition, Dhruv publications, 2005.4. V. K. Ahluwalia, Lalita S. Kumar and Sanjiv Kumar, Chemistry of Natural Products, Ane Books India.5. L. P. Graham An introduction to Medicinal Chemistry, 3rd edition, Oxford University Press, 2005.