Back close

Computational Modelling of Neurotransmitter Mediated Motor Learning in Basal Ganglia

Project Incharge:Dr. Manjusha Nair M.
Co-Project Incharge:Dr. Shyam Diwakar
Computational Modelling of Neurotransmitter Mediated Motor Learning in Basal Ganglia

Neurotransmitters are chemical messengers that carry signals from one neuron to the next and even to muscles or glands. In recent years several computational and mathematical analysis of the model has been widely used to study the dysfunction of Basal Ganglia (BG). The proposed study focuses on the neural dynamics of Neurotransmitters associated with motor learning in Basal Ganglia. This study will implement an artificial Reinforcement learning model which explains the dynamic behavior of Parkinson’s Disease, a neurological condition associated with the lesion of the Basal Ganglia and thereby bridging the gap between Artificial Intelligence (AI) and Neuroscience. The demonstration of the condition of Parkinson’s Disease under the context of reinforcement learning is planned with the help of a robotic arm or a virtual robot. The Reinforcement Learning model should automatically select an indirect pathway by learning the factors causing the depletion of neurons and thus inhibiting the movements or generating motor symptoms like tremor. In addition to this, a 3-Dimensional demonstration of the excitation and inhibition of the neurons in the PD condition will be done with the help of Unity Real-time Development Platform, for better understanding.

Related Projects

Mass Spectrometric Characterization of Bioactive Peptides and Proteins
Mass Spectrometric Characterization of Bioactive Peptides and Proteins
Deep Learning based Automated ASPECT Score and Infarct Core Prediction for Stroke Patients
Deep Learning based Automated ASPECT Score and Infarct Core Prediction for Stroke Patients
ROS Based Autonomous Shopping Cart with e-Payment Facility
ROS Based Autonomous Shopping Cart with e-Payment Facility
Investigation of compatibility between portland pozzolana cement and admixtures in high performance concrete
Investigation of compatibility between portland pozzolana cement and admixtures in high performance concrete
Targeted Nanoparticle Photodynamic Therapy
Targeted Nanoparticle Photodynamic Therapy
Admissions Apply Now