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Course Detail

Course Name Pharmaceutical Organic Chemistry Practical
Course Code PD.112P
Program Pharm. D.
Campus Kochi

Syllabus

LIST OF EXPERIMENTS:

  1. Preparation of Benzanilide by Schotten-Baumann reaction
  2. Preparation of Salicylic acid from methyl salicylate by hydrolysis
  3. Preparation of Aspirin by acetylation of salicylic acid
  4. Preparation of Dibenzal acetone by a cross-aldol condensation reaction, or Claisen- Schmidt reaction
  5. Preparation of Meta Dinitrobenzene by nitration of nitrobenzene
  6. Preparation of 1-Phenyl Azo-2-naphthol by diazotization and coupling reaction
  7. Determination of Melting Point and Boiling Point
  8. Detection of elements (Nitrogen & sulphur) present in the sample
  9. Systematic qualitative analysis of unknown organic sample (Resorcinol)
  10. Systematic qualitative analysis of unknown organic sample (Urea)
  11. Systematic qualitative analysis of unknown organic sample (Thiourea)
  12. Systematic qualitative analysis of unknown organic sample (Amines)
  13. Systematic qualitative analysis of unknown organic sample (Cinnamic Acid)
  14. Systematic qualitative analysis of unknown organic sample (Benzaldehyde)
  15. Systematic qualitative analysis of unknown organic sample (Methyl salicylate)

 

SEMINAR/ASSIGNMENTS

  1. Principle of confirmatory test for various organic functional groups such as carboxylic acid, alcohol, phenol, aldehydes, ketones, amines, amides.
  2. Various synthetic applications of name reactions like aldol condensation, Hoffman rearrangement
  3. Basic principle of addition, substitution, elimination
  4. Medicinal uses of some important organic
  5. General principle for purification of organic synthetic

Text Books / References

TEXT BOOKS:

  1. Morrison, T., & Boyd, R. N and Bhattacharjee. Organic chemistry. 7th ed. Pearson Education India; 2010.
  2. Arun Bahl and S. Bahl. A textbook of organic chemistry. 22nd ed. S. Chand; 2016.
  3. L. Soni & H. M. Chawla. Textbook of organic chemistry. 29th edn. Sultan Chand & son: India; 2012.
  4. P. Agarwal. Organic chemistry: reactions and reagents. 56th edn. Goel Publishing House. 2018

REFERENCE BOOKS:

  1. Mann G & Saunders B C. Practical organic chemistry. 4th edn. Pearson Education India; 2009
  2. Bruice Y. Organic Chemistry. 8thedn.Upper Saddle River, NJ: Pearson Education; 2015.
  3. Brian F, Antony J.H, Peter W.G.S & Austin R.T. Vogel’s textbook of Practical Organic Chemistry. 5th edn. Pearson Education India; 2003.
  4. Donald Pavia, Gary M. Lampman, George S. Krizet al. A small-scale approach to organic laboratory techniques. U.S: Cengage Learning; 2014.

 

*Latest edition of the text books & reference books can be referred

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