Back close

Diversity Oriented Synthesis Applications to Flavonols, Flavones, Isoflavones and Biflavones

Start Date: Sunday, Mar 01,2009

School: School of Biotechnology

Funded by:Amrita Vishwa Vidyapeetham
Diversity Oriented Synthesis Applications to Flavonols, Flavones, Isoflavones and Biflavones

Divergent oriented synthesis is a strategy which aims to the synthesis of compounds with diverse chemical structures. It is often an alternative to convergent synthesis or linear synthesis. With this intention, the diversity oriented synthesis was developed. In Phytochemistry laboratory our aims is to generate a library of bioactive oxygen heterocyclic compounds by first reacting with a easily available starting material to form set of intermediates, e.g. chalcones, 1,3-diketones.  The next target compounds are generated by suitable transformations of  intermediates, e.g. flavones, flavonols, flavanones, isoflavones and biflavones. This methodology quickly diverges to large numbers of different classes of compounds from simple starting materials. It is also efficient synthesis. The scheme methodology is given below.

diversity-bio-project

Some examples of  compounds synthesised are given below:

  1. chalcones
  2. dihydroflavonols
  3. flavones
  4. flavonol 
  5. isoflavones

Related Projects

Transformation, Expression and Activity Analysis of Recombinant Staphylococcus Autolysin in Bacillus
Transformation, Expression and Activity Analysis of Recombinant Staphylococcus Autolysin in Bacillus
Studies on Binding of Probiotic Strains to Host Extracellular Matrix Protein, Gelatin and Analysis of its Stability with Different Substrates
Studies on Binding of Probiotic Strains to Host Extracellular Matrix Protein, Gelatin and Analysis of its Stability with Different Substrates
Green Synthesis of Metal Nanoparticles & its Applications
Green Synthesis of Metal Nanoparticles & its Applications
Development of Host-directed Therapies for Drug Resistant Klebsiella Pneumonia Infections
Development of Host-directed Therapies for Drug Resistant Klebsiella Pneumonia Infections
Screening, Identification and Characterisation of Bacteriocins Isolated from Wine Microflora
Screening, Identification and Characterisation of Bacteriocins Isolated from Wine Microflora
Admissions Apply Now