Back close

Diversity Oriented Synthesis Applications to Flavonols, Flavones, Isoflavones and Biflavones

Start Date: Sunday, Mar 01,2009

School: School of Biotechnology

Funded by:Amrita Vishwa Vidyapeetham
Diversity Oriented Synthesis Applications to Flavonols, Flavones, Isoflavones and Biflavones

Divergent oriented synthesis is a strategy which aims to the synthesis of compounds with diverse chemical structures. It is often an alternative to convergent synthesis or linear synthesis. With this intention, the diversity oriented synthesis was developed. In Phytochemistry laboratory our aims is to generate a library of bioactive oxygen heterocyclic compounds by first reacting with a easily available starting material to form set of intermediates, e.g. chalcones, 1,3-diketones.  The next target compounds are generated by suitable transformations of  intermediates, e.g. flavones, flavonols, flavanones, isoflavones and biflavones. This methodology quickly diverges to large numbers of different classes of compounds from simple starting materials. It is also efficient synthesis. The scheme methodology is given below.

diversity-bio-project

Some examples of  compounds synthesised are given below:

  1. chalcones
  2. dihydroflavonols
  3. flavones
  4. flavonol 
  5. isoflavones

Related Projects

MFC- Caulobactercrescentus as an Electrogen in A Dual Chambered Microbial Fuel Cell With The Novel Proton Exchange Membrane
MFC- Caulobactercrescentus as an Electrogen in A Dual Chambered Microbial Fuel Cell With The Novel Proton Exchange Membrane
MIMIC – A Unique approach to wound healing assays
MIMIC – A Unique approach to wound healing assays
Glucosamine Conjugated Chitosan Derivatives- Synthesis and Study of Antimicrobial Activity
Glucosamine Conjugated Chitosan Derivatives- Synthesis and Study of Antimicrobial Activity
Lab-on-a-chip(LOC) for the monitoring of diabetes, cholesterol and kidney function
Lab-on-a-chip(LOC) for the monitoring of diabetes, cholesterol and kidney function
Inventory of Vegetation with special reference to Medicinal and Aromatic Plants and Documentation of Traditional Knowledge – in the Walayar Valley, Western Ghats
Inventory of Vegetation with special reference to Medicinal and Aromatic Plants and Documentation of Traditional Knowledge – in the Walayar Valley, Western Ghats
Admissions Apply Now