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Diagnosis and management of pediatric acute liver failure: consensus recommendations of the Indian Society of Pediatric Gastroenterology, Hepatology, and Nutrition (ISPGHAN)

Publication Type : Journal Article

Publisher : Springer Science and Business Media LLC

Source : Hepatology International

Url : https://doi.org/10.1007/s12072-024-10720-3

Campus : Faridabad

School : School of Medicine

Year : 2024

Abstract : Timely diagnosis and management of pediatric acute liver failure (PALF) is of paramount importance to improve survival. The Indian Society of Pediatric Gastroenterology, Hepatology, and Nutrition invited national and international experts to identify and review important management and research questions. These covered the definition, age appropriate stepwise workup for the etiology, non-invasive diagnosis and management of cerebral edema, prognostic scores, criteria for listing for liver transplantation (LT) and bridging therapies in PALF. Statements and recommendations based on evidences assessed using the modified Grading of Recommendations Assessment, Development and Evaluation (GRADE) system were developed, deliberated and critically reappraised by circulation. The final consensus recommendations along with relevant published background information are presented here. We expect that these recommendations would be followed by the pediatric and adult medical fraternity to improve the outcomes of PALF patients.

Cite this Research Publication : Bikrant Bihari Lal, Rajeev Khanna, Vikrant Sood, Seema Alam, Aabha Nagral, Aathira Ravindranath, Aditi Kumar, Akash Deep, Amrit Gopan, Anshu Srivastava, Arjun Maria, Arti Pawaria, Ashish Bavdekar, Gaurav Sindwani, Kalpana Panda, Karunesh Kumar, Malathi Sathiyasekaran, Maninder Dhaliwal, Marianne Samyn, Maya Peethambaran, Moinak Sen Sarma, Moreshwar S. Desai, Neelam Mohan, Nirmala Dheivamani, Piyush Upadhyay, Pratibha Kale, Rakhi Maiwall, Rohan Malik, Roshan Lal Koul, Snehavardhan Pandey, Somashekara Hosaagrahara Ramakrishna, Surender Kumar Yachha, Sadhna Lal, Sahana Shankar, Sajan Agarwal, Shivani Deswal, Smita Malhotra, Vibhor Borkar, Vipul Gautam, Viswanathan M. Sivaramakrishnan, Anil Dhawan, Mohamed Rela, Shiv Kumar Sarin, Diagnosis and management of pediatric acute liver failure: consensus recommendations of the Indian Society of Pediatric Gastroenterology, Hepatology, and Nutrition (ISPGHAN), Hepatology International, Springer Science and Business Media LLC, 2024, https://doi.org/10.1007/s12072-024-10720-3

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