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Subcutaneous mycosis caused by filamentous basidiomycete Megasporoporia setulosa-first report of human infection

Publication Type : Case Reports

Publisher : Elsevier BV

Source : Medical Mycology Case Reports

Url : https://doi.org/10.1016/j.mmcr.2023.07.002

Keywords : Subcutaneous mycosis, Megasporoporia setulosa, Filamentous basidiomycetes, DNA sequencing, Molecular phylogeny

Campus : Faridabad

School : School of Medicine

Department : Microbiology

Year : 2023

Abstract :

Filamentous basidiomycetes are an emerging cause of human infection in tropical and subtropical regions. We report a case of subcutaneous infection caused by the shelf fungus, Megasporoporia setulosa, in an immunocompetent male. This is also the first report of human infection caused by this filamentous basidiomycete. Identification of the fungus could only be achieved by sequencing the ITS and LSU regions of rDNA. The patient recovered following surgery and treatment with amphotericin B and oral itraconazole. This report underscores the cross-kingdom pathogenicity of plant fungi and the importance of molecular tools for definitive identification of nonsporulating fungal species.

Cite this Research Publication : Arghadip Samaddar, Twishi Shrimali, Anuradha Sharma, Subcutaneous mycosis caused by filamentous basidiomycete Megasporoporia setulosa-first report of human infection, Medical Mycology Case Reports, Elsevier BV, 2023, https://doi.org/10.1016/j.mmcr.2023.07.002

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