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Photophysical and Co-ordination Properties of Cyclam Core Dendrimers
Photophysical and Co-ordination Properties of Cyclam Core Dendrimers

As part of the India 4 EU program, Dr. Zeena S. Pillai, Department of Chemistry, Amrita School of Arts and Sciences, had the opportunity to work at the University of. . .

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Macrocyclic and Carbocyclic Constructions by SET Oxidations of Styrenes, Allenes and Cyclopropanes
Macrocyclic and Carbocyclic Constructions by SET Oxidations of Styrenes, Allenes and Cyclopropanes

The project titled, “Macrocyclic and Carbocyclic Constructions by SET Oxidations of Styrenes, Allenes and Cyclopropanes”  was sanctioned by the  Department of Science and Technology with budget of  17 lakhs.   

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Proteasome inhibitors from natural products
Proteasome inhibitors from natural products

The ubiquitin-proteasome system (UPS) plays an essential role in many cellular processes, including cell cycle progression, proliferation, apoptosis and angiogenesis. Proteasome inhibitors like Bortezomib (Velcade, PS-341), has been successfully used. . .

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In vitro assay of theranostic agents and their targeted delivery
In vitro assay of theranostic agents and their targeted delivery

This work is in collaboration with Dr. Sankarprasad Bhuniya, Amrita Center for Industrial Research and Innovation (ACIRI), Amrita University, Coimbatore. His lab synthesizes synthetic derivatives with therapeutic as well as diagnostic. . .

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Mitochondrial dynamics
Mitochondrial dynamics

Mitochondria continually undergo fusion and fission along with motility responding to cellular signaling. Our goal is to systematically evaluate the regulatory switches that govern the dynamics. Although the machineries mediating. . .

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Paraptosis: a non-apoptotic cell death pathway to target cancer
Paraptosis: a non-apoptotic cell death pathway to target cancer

Many cancer cells develop resistance to the apoptotic signals and flourish in the system. We are trying to target these defiant cells by inducing an alternative cell death pathway through. . .

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Center of Excellence in Advanced Materials and Green Technologies
Center of Excellence in Advanced Materials and Green Technologies

The Centre for Materials Research will engage in research and development activities in the broad areas encompassing the individual developments in, or an integration of, advanced materials and green technologies. . .

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MIMIC – A Unique approach to wound healing assays
MIMIC – A Unique approach to wound healing assays

Nowadays researchers are interested in cell patterning and here is a method used for patterning mammalian cells that does not require access to photolithographic capabilities. This work describes a versatile. . .

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Modulation of fibrino(geno)lytic proteases from Russell’s viper venom using natural products and analogs
Modulation of fibrino(geno)lytic proteases from Russell’s viper venom using natural products and analogs

Envenomation incapacitates the snake’s prey by interfering with specific aspects of physiological function such as nerve transmission and hemostasis.  Since the action of venom components is highly specific, many venom. . .

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