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Course Detail

Course Name Cell Culture and Tissue Engineering
Course Code 24AIM432
Semester VI
Credits 3
Campus Coimbatore


Unit 1

Fundamental Of Tissue Engineering Fundamentals Of Stem Cell Tissue Engineering; Growth Factors; Extracellular Matrix: Structure, Function And Tissue Engineering Application; Mechanical Forces On Cells; Cell Adhesion; Cell Migration.

Unit 2

Tissue Engineering Enabling Technologies Polymer Scaffold For Tissue Engineering Applications; Biomimetic Materials; Nanocomposite Scaffolds Tissue Engineering; Bioreactors; Regulatory Issues In Tissue Engineering.

Unit 3

Tissue Engineering Application I Bioengineering Of Human Skin Substitute; Nerve Tissue Engineering; Musculoskeletal Tissue Engineering; Bone Tissue Engineering; Cartilage Tissue Engineering; Temporomandibular Tissue Engineering; Smooth Muscle Tissue Engineering; Esophagus Tissue Engineering.

Unit 4

Tissue Engineering Application II Vascular Graft Tissue Engineering Cardiac Tissue Engineering; Heart Valve Tissue Engineering; Urologic Organ Tissue Engineering; Hepatic Tissue Engineering; Renal Tissue Engineering; Dental Tissue Engineering; Tracheal Tissue Engineering.

Course Objectives and Outcomes

Course Objectives:

  • To make students understand the Basic Utility and Potential of Tissue Engineering Principles.
  • To Create Problem Solving Ability Among Students for Developing Strategies to Build Tissue Engineering Solutions.
  • To Encourage Students for Fabricating Tissue Engineering Products.

Course Outcomes:

After completing this course, students should be able to
CO1: Understand the fundamentals of stem cell tissue engineering, growth factors, and the role of extracellular matrix in tissue engineering applications.
CO2: Explore enabling technologies such as polymer scaffolds, biomimetic materials, nanocomposites, and bioreactors used in tissue engineering.
CO3: Apply tissue engineering concepts to various applications including human skin, nerve, musculoskeletal, bone, cartilage, temporomandibular, and smooth muscle tissue engineering.
CO4: Examine advanced tissue engineering applications like vascular grafts, cardiac, heart valve, urologic organ, hepatic, renal, dental, and tracheal tissue engineering, considering regulatory issues.

CO-PO Mapping



PO 1 PO2 PO3 PO4 PO5 PO 6 PO7 PO8 PO 9 PO 10 PO 11 PO 12 PSO 1 PSO2 PSO3
CO1 1 2 1 2 2 2 3 3 3
CO2 1 2 1 3 2 2 2 3 3 3
CO3 1 1 1 1 2 2 2 3 3 3
CO4 1 3 1 2 2 2 2 3 3 3


  1. Clemens van Blitterswijk, Tissue Engineering, Academic Press, 2008.
  2. Lanza, R., Langer, R., Vacanti, J. P., & Atala, A. (Eds.), Principles of tissue engineering. Academic press, 2020.
  3. Palsson, B., Hubbell, J. A., Plonsey, R., & Bronzino, J. D., Principles, and applications in engineering series. Tissue Engineering, CRC Press, Boca Raton, FL, 2003

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