Qualification: 
MD, BAMS
drprajeeshnath@am.amrita.edu

Dr. Prajeesh Nath E. N. currently serves as Assistant Professor in the Department of Rasasashtra and Bhaishajya Kalpana and with the additional responsibility of Research Officer in ACARA, Amrita School of Ayurveda. He pursued his BAMS and Post graduation from Amrita School of Ayurveda. Dr. Prajeesh worked as Clinical Registrar, Department of Panchakarma and Shalakya, Amrita School of Ayurveda, Kollam, during 2011-2012.

Publications

Publication Type: Journal Article

Year of Publication Title

2020

C. Pushkaran Anju, Prajeeshnath E. N., Shantikumar V Nair, Ram Manohar P., and Dr. Gopi Mohan C., “Structure-Based Bioactive Phytochemical Design from Ayurvedic Formulations Towards Spike and Mpro Druggable Targets of SARS-CoV-2”, ChemRxi, 2020.[Abstract]


Since the emergence of novel Coronavirus(SARS-CoV-2) infection in Wuhan, China in December 2019, it has now spread to over 205 countries. The ever-growing list of globally spread corona virus-19 disease (COVID19) patients has demonstrated the high transmission rate among human population. Although 12 new drugs are being tried for management of COVID19, currently there are no FDA approved drugs or vaccines to prevent and treat the infection of the SARS-CoV-2. Considering the current state of affairs, there is an urgent unmet medical need to identify novel and effective approaches for prevention and treatment of COVID19 by re-evaluating the knowledge of traditional medicines and repurposing of drugs. Here, we used molecular docking approach to explore the beneficial roles of an array of phytochemicals and active pharmacological agents present in the Indian herbs (Tulsi, Haldi, Giloy, Black pepper, Ginger, Clove, Cardamom, lemon, and Ashwagandha) which are widely used in the preparation of Ayurvedic medicines in the form of Kadha to control various respiratory disorders such as cough, cold and flu. The evaluation was made based on the docking scores calculated by AutoDock Vina. Our study has identified an array of phytochemicals present in these herbs which have significant docking scores and potential to inhibit different stages of SARS-CoV-2 infection as well as other Coronavirustarget proteins. Molecular docking also indicated that, the phytochemicals present in these herbs possess significant anti-inflammatory property. Overall our study providesscientific justification in terms of binding of active ingredients present in different plants used in Kadhapreparation with viral proteins and target proteinsfor prevention and treatment of the COVID19.This preparation can boost individual’simmunity and inhibit the viral severity by interfering at different stages of virus multiplication in the infected person.

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2018

Prajeeshnath E. N., Dr. Sushma, and Shyamasundaran K., “Concept of Immunomodulators in Cancer Treatment: An Ayurveda Outlook, AYU Journal(On Process)”, 2018.

2018

Dr. Sushma, Minsha, M. G., Sreelekshmi, R., and Prajeeshnath E. N., “Variations in UV-Vis spectra of Hot and Cold infusions of Triphala choorna, J-AIM (On Process)”, 2018.

2016

Prajeeshnath E. N., NV, D. Ramesh, and Dr. Arun Mohanan, “An overview on Gandhaka kalpa and its rasayana effect”, Paryeshana International Journal of Ayurvedic Research (PIJAR), vol. I, no. II, 2016.[Abstract]


Living healthy is the prime motto of this era but increased use of antibiotics and immuno- suppressive drugs, sedentary life, the quality of life get affected. Many kalpas have been described in Rasashastra for the conservation of immunity, physical and pshycological state of the body. In the field Rasayana, Gandhaka holds top after Parada. It possess ‘Katu’ rasa, ‘Ushna’ virya and Pachaka karma. Sudha Gandhaka when consume for many days with suitable adjuvant will provide good eye sight and improves jataragni. It is a good Rasyana also. Acharya Charaka has described Rasayana as a means to promote vigor and health which is mainly virilific and promotive of vitality. In the eighth chapter of Rasatarangini mentions 10 Gandhaka Kalpas. By judicious use of these kalpas, the person attains divyadrishti (sharp eye sight), suvarna kaya (golden radiance in the body), virya (high virility) and shaurya (physical strength) even in aged persons, vajra kaya (sturdy body), cures vali and palita roga (hair fall and hair greying), and also cures many of the chronic Kaphaja, Vataja and Pittaja rogas.

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Publication Type: Conference Paper

Year of Publication Title

2019

Prajeeshnath E. N., Ramesh, N. V., and Dr. Arun Mohanan, “Concept of Immunomodulators in Cancer Treatment: An Ayurveda Outlook”, in IASTAM Oration and Award Function 2019 & Conclave on Cancer Care & Research in AYUSH: Developing a Roadmap , Amrita Institute of Medical Sciences, Kochi, 2019.

2019

Prajeeshnath E. N., “Gokshura as a rich source of Aphrodisiac Phytoconstituent Protodioscin : A Literary review”, in National Seminar on Management of Infertility in Ayurveda, Prajnanam 2019 , Amrita School of Ayurveda, Amrita Vishwa Vidyapeetham, Kollam, 2019.

2018

Prajeeshnath E. N., “A critical analysis of the mode of action of Avipathi gutika and Avipattikar churna on the basis of their formulation and administration”, in Jignasa, Banglore, 2018.

2018

Prajeeshnath E. N., “Variations in UV Vis spectra of hot and cold infusions of Triphala choorna”, in 8th World Ayurveda Congress, Ahmedabad, 2018.

2018

Prajeeshnath E. N., “Neutraceuticals and Rasayanachikitsa in Ayurveda”, 2018.

2016

Prajeeshnath E. N., “Role of Snehakalpana in the Management of Neurodegenerative Diseases”, 2016.

2015

Prajeeshnath E. N., “An overview on Gandhaka kalpa and its rasayana effect.”, 2015.[Abstract]


Living healthy is the prime motto of this era but increased use of antibiotics and immuno- suppressive drugs, sedentary life, the quality of life get affected. Many kalpas have been described in Rasashastra for the conservation of immunity, physical and pshycological state of the body. In the field Rasayana, Gandhaka holds top after Parada. It possess ‘Katu’ rasa, ‘Ushna’ virya and Pachaka karma. Sudha Gandhaka when consume for many days with suitable adjuvant will provide good eye sight and improves jataragni. It is a good Rasyana also. Acharya Charaka has described Rasayana as a means to promote vigor and health which is mainly virilific and promotive of vitality. In the eighth chapter of Rasatarangini mentions 10 Gandhaka Kalpas. By judicious use of these kalpas, the person attains divyadrishti (sharp eye sight), suvarna kaya (golden radiance in the body), virya (high virility) and shaurya (physical strength) even in aged persons, vajra kaya (sturdy body), cures vali and palita roga (hair fall and hair greying), and also cures many of the chronic Kaphaja, Vataja and Pittaja rogas.

More »»