Publication Type : Journal Article
Thematic Areas : Nanosciences and Molecular Medicine
Publisher : Handbook of Immunological Properties of Engineered Nanomaterials
Source : Handbook of Immunological Properties of Engineered Nanomaterials, p.477-516 (2016)
Url : https://www.worldscientific.com/doi/abs/10.1142/9789814390262_0016
Campus : Kochi
School : Center for Nanosciences
Center : Amrita Center for Nanosciences and Molecular Medicine Move, Nanosciences
Department : Nanosciences and Molecular Medicine
Year : 2016
Abstract : Abstract The ever-exploding scientific advancements in the field of nanotechnology have enabled its integration into biosciences and medicine. Such interdisciplinary approaches allow researchers to engineer novel tools for diagnosis, therapy, and prognosis of different clinical complications. One of the most successful nano-tools that have emerged in recent years are nano-drug delivery devices. The use of such nano-sized carriers to load therapeutic agents (drugs, vaccines, biomolecules, and enzymes) aid in overcoming their pharmacological and toxicological hurdles through site-specific and controlled drug delivery. This chapter is a comprehensive account on the recent developments in the delivery of anti-inflammatory drugs using nanocarriers. Here, various kinds and types of nanocarriers and their countless inherent and engineered properties which make them ideal for delivering anti-inflammatory drugs, and the special characteristics of inflammation and inflammatory cells and tissues, which make them vulnerable to these nano-tools, will be discussed. The potential active and passive targeting approaches using drug-loaded nanocarriers for various inflammatory disorders are also elaborated.
Cite this Research Publication : D. Menon, Gopikrishna, J., Narayanan, D., and Shantikumar V. Nair, “Nanoparticles as Drug Delivery Vehicles for the Therapy of Inflammatory Disorders”, Handbook of Immunological Properties of Engineered Nanomaterials, pp. 477-516, 2016.