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Publication Type : Conference Proceedings
Publisher : Elsevier
Source : 19th CRSI National Symposium in Chemistry, July 14-16, 2016, Darjeeling, India.
Url : https://www.sciencedirect.com/science/article/abs/pii/S0040403916307626
Campus : Amritapuri
School : School of Biotechnology
Verified : No
Year : 2016
Abstract : Glycolate alkylation reactions of (S)-4-isopropyl-1-[(R)-1-phenylethyl]imidazolidin-2-one auxiliary has been optimised with high yields and diastereoselectivity on substituted benzyl and allyl bromides. The standardised reaction condition was employed for the stereoselective synthesis of EEHP and EMHP intermediates of PPAR agonists.
Cite this Research Publication : Vipin A Nair, "A highly efficient enantioselective synthesis of EEHP and EMHP: intermediates of PPAR agonists", 19th CRSI National Symposium in Chemistry, July 14-16, 2016, Darjeeling, India.