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Publication Type : Journal Article
Publisher : J. K. Welfare and Pharmascope Foundation
Source : International Journal of Research in Pharmaceutical Sciences, J. K. Welfare and Pharmascope Foundation, Volume 10, Number 2, p.874-882 (2019)
Campus : Kochi
School : School of Pharmacy
Department : Pharmaceutics
Year : 2019
Abstract : The target of the study was the development and in vitro characterisation of an effective ethosomal formulation of clotrimazole and to the performance of the formulation was investigated under different preparation conditions. The EE and from 9 formulations, the optimisation was done on the basis of its results which considering the concentration of lecithin and ethanol as the two factors and EE and in vitro release as their responses. The optimization was done on the basis of its results which considering the concentration of lecithin and ethanol as the two factors and EE and in vitro release as their responses. F6 formulation gained a very good release of drug and highest entrapment efficiency of 93.203%. The results of permeation flux were obtained in the order of MLVs > ESUVs > SSUVs > LUVs. This study gives an idea about the vesicles structure and the size, the technique used, the drug EE and the permeation rate. They were taking the above factors into consideration results in improving clinical effectiveness in transdermal delivery of an ethosomal formulation of clotrimazole. © 2018 Pharmascope Publications. All rights reserved.
Cite this Research Publication : Dr. Vidya Viswanad, Anju, P. G., Kumar, G. S., and Nair, S. C., “Formulation development and in-vitro characterisation of ethosomes for the enhanced transdermal delivery of clotrimazole”, International Journal of Research in Pharmaceutical Sciences, vol. 10, pp. 874-882, 2019.