Syllabus
Unit I
Drugs and Pharmaceuticals (14 hours)Drug discovery, design and development; Basic Retrosynthetic approach. Synthesis of the representative drugs of the following classes: analgesics agents, antipyretic agents, anti-inflammatory agents (Aspirin, paracetamol, lbuprofen); antibiotics (Chloramphenicol); antibacterial and antifungal agents (Sulphonamides; Sulphanethoxazol, Sulphacetamide, Trimethoprim); antiviral agents (Acyclovir), Central Nervous System agents (Phenobarbital, Diazepam),Cardiovascular (Glyceryl trinitrate), antilaprosy (Dapsone), HIV-AIDS related drugs (AZT- Zidovudine).
Unit II
0
Text Books / References
TEXTBOOKS / REFERENCES:1) E. Stocchi: Industrial Chemistry, Vol -I, Ellis Horwood Ltd. UK.2) P.C. Jain, M. Jain: Engineering Chemistry, Dhanpat Rai & Sons, Delhi.3) B.K. Sharma: Industrial Chemistry, Goel Publishing House, Meerut.4) G.L. Patrick: Introduction to Medicinal Chemistry, Oxford University Press, UK.5) Hakishan, V.K. Kapoor: Medicinal and Pharmaceutical Chemistry, Vallabh Prakashan, Pitampura, New Delhi.6) R. Cremlyn: Pesticides, John Wiley.7) William O. Foye, Thomas L., Lemke , David A. William: Principles of Medicinal Chemistry, B.I. Waverly Pvt Ltd. New Delhi.
