Publication Type : Journal Article
Publisher : Indian Journal of Clinical Biochemistry
Source : Indian Journal of Clinical Biochemistry, Volume 13, Number 2, p.126-128 (1998)
Campus : Kochi
School : School of Medicine
Year : 1998
Abstract : In a pilot study with five oral cancer patients undergoing radiotherapy (RT) three were given Granulocyte Macrophage Colony Stimulating Factor (GM-CSF) as a protective agent to reduce the mucosal inflammation during radiotherapy. The myeloperoxidase (MPO) enzyme activity in WBC was quantitated. The three patients snowed a significant increase in the MPO activity when compared with two untreated controls indicating the efficacy of GM-CSF as a protective agent. It is suggested that further detailed studies with larger number of patients would be useful.
Cite this Research Publication : N. Ananth, B. Balaji Ganesh, D.M. Vasudevan, Vivian D’Souza, Ashalatha V. Rao, and Dinesh Nambiar, "Enhancement of Myeloperoxidase activity in WBCs in patients treated with Granulocyte Macrophage Colony Stimulating Factor (GM-CSF), a pilot study," Indian J. Clinical Biochemistry, 13, 126-128, 1998. PMID: 23105194; DOI: 10.1007/BF02867875