Course

Unit 1

Molecules of life (Structural Biochemistry: sugars, amino acids, nucleic acids, carbohydrates, lipids, etc. and their polymers)

Unit 2

Sub-cellular organizations & architectures (Cell Biology: membrane, nucleus, golgi apparatus, cytoskeleton, etc.) & tissues, organs, and systems (General morphology/histology/anatomy, particularly human)

Unit 3

Classical enzymology & murzymes; basics of routine metabolism (thermodynamics, kinetics, structure-function correlations)

Unit 4

Comprehensive overviews on organization of life (cell theory, central dogma and murburn concept)

Course Objectives:

• Develop a foundational understanding of the structural biochemistry of essential biomolecules, including sugars, amino acids, nucleic acids, carbohydrates, and lipids, along with their polymers.
• Explore the sub-cellular organizations and architectures, delving into cell biology concepts related to membranes, nuclei, golgi apparatus, cytoskeleton, tissues, organs, and systems, with a focus on human morphology, histology, and anatomy.
• Gain insights into classical enzymology, murzymes, and the basics of routine metabolism, including principles of thermodynamics, kinetics, and structure-function correlations.
• Acquire comprehensive overviews of the organization of life, encompassing cell theory, the central dogma, and the murburn concept.

Course Outcomes:
After completing this course, students should be able to

• CO1: Apply knowledge of structural biochemistry to identify and understand the functions of essential biomolecules and their polymers.
• CO2: Analyze and comprehend the sub-cellular structures and organizations, including membranes, nuclei, golgi apparatus, cytoskeleton, tissues, organs, and systems, with a specific emphasis on human morphology, histology, and anatomy.
• CO3: Demonstrate a clear understanding of classical enzymology, murzymes, and routine metabolism, applying principles of thermodynamics, kinetics, and structure-function correlations.
• CO4 : Integrate knowledge of the organization of life, including cell theory, the central dogma, and murburn concept, providing a comprehensive understanding of fundamental biological processes.

CO-PO Mapping

1. Nelson, D.L. and Cox, M.M. (2017) Lehninger Principles of Biochemistry. 7th Edition, W.H. Freeman, New York, 1328.
2. Basic concepts in biochemistry: A student’s survival guide by Hiram F Gilbert. pp 298. McGraw-Hill, NY. 1992.
3. Bruce Alberts … [and others]. Molecular Biology of the Cell. New York :Garland Pub., 1989.
4. Pelczar, M.J., Chan, E.C.S. and Kreig, N.R. (2002) Microbiology. 5th Edition, Tata McGraw-Hill, New Delhi.
5. Mescher A.L.(Ed.), [publicationyear2] Junqueira’s Basic Histology: Text and Atlas, 15e. McGraw-Hill Education. https://accessmedicine.mhmedical.com/content.aspx?bookid=2430&sectionid=190220001
6. Richard L. Drake, A. Wayne Vogl, Adam W. M. Mitchell. Gray’s anatomy for students. Elsevier. ISBN : 9780323934237
7. Murburn concept in cellular function and bioenergetics: Part 1: Understanding murzymes at the molecular level. https://doi.org/10.1063/5.0171857 Manoj et al.
8. Murburn concept in cellular function and bioenergetics: Part 1: Understanding integrations-translations from molecular to macroscopic levels. https://doi.org/10.1063/5.0171860 Manoj et al.