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Dr. Manzoor K.

Professor

Manzoor Koyakutty is a Professor at the Amrita Centre for Nanosciences and Molecular Medicine, Cochin, India. He specializes in the area of Cancer nanomedicine & Immunotherapeutics.

Qualification: Ph.D
manzoork@aims.amrita.edu

Bio

Manzoor Koyakutty is a Professor at the Amrita Centre for Nanosciences and Molecular Medicine, Cochin, India. He specializes in the area of Cancer nanomedicine & Immunotherapeutics. Dr. Manzoor joined ACNS during June 2007 after 9 years of service as Staff-Scientist at the Defence Research and Development Organization (DRDO), Government of India. During this tenure, he completed Ph. D. in Physics (Nanoscience) from DRDO (JNVU, Jodhpur) under the guidance of Dr. S. R. Vadera, Director, DRDO and Prof. T. R. N. Kutty, Indian Institute of Science, Bangalore. After shifting to Amrita, Dr. Manzoor’s team focused on the area of cancer-nanomedicine and developed many novel nano-systems to interfere with the complex biology of cancer. With the emergence of cancer-immunotherapy, his team also work on activating the immune system against cancer using novel nano-immunomedicines. Specific areas of research include: nanomedicines for drug -radiation resistant cancer and cancer stem cells, brain implantable nanomedicine for prolonged drug-delivery, nanoparticle-based image guided radio-wave therapy and photodynamic therapy, cancer immunotherapy using dendritic cells (DC), neo-mRNA nano-vaccines, Raman spectral imaging of cancer, application of artificial intelligence (IA) in nanomedicine and immunotherapy. He has 32 international patents (10 issued in USA/ Japan/China/Europe) and published more than 65 peer reviewed research papers in nanomedicine. Three IPs are licenced to pharma companies for commercial development. He serves as Associate Editor of the Journal: Precision Nanomedicine (European Foundation for Clinical Nanomedicine-CLINAM). He also served in the editorial board member of the journal Nanomedicine: NBM (Elsevier). He is an expert member in ‘Translational Nano-Biotechnology’ Task force, Dept. of Biotechnology, Govt of India. He is a co-founder of the bio-pharma start-up company M/s LuxMatra Innovations Pvt. Ltd, C-Camp, Bangalore.

Awards / Recognitions

  • 2003 DRDO Laboratory Scientist of the Year
  • 2004 DRDO Young Scientist Award
  • 2006 DRDO Technology Developer Award
  • 2003 National Science Day Award for best scientific publication, DRDO
  • 2004 National Science Day Award for best scientific publication, DRDO
  • 2005 National Science Day Award for best scientific publication, DRDO
  • 2006 National Science Day Award for best scientific publication, DRDO
  • 2007 Marie Curie International Incoming Fellowship (IIF), FP-7
  • 2013 Best Reviewer award, Journal Nanomedicine: NBM
  • 2014 Taskforce Member: RNAi Program, Govt of India
  • 2014 Taskforce Member: NanoBiotechnology Program, Govt of India
  • 2017 Fellow of National Academy of Sciences, FNASc (Biological Sciences)
  • 2018 Taskforce Member: Translational Nanomedicine Program, DBT, Govt of India
  • 2018 Assoc. Editor, Journal Precision nanomedicine (Eur. Found. for Clinical Nanomedicine)

Research Projects

  • Nano-fiber brain implant for prolonged and localized delivery of anti-glioma drugs: Funding by TPF-Nanomission, Dept of Sci & Tech (DST), India
  • Nanoparticle based gene editing using CRISPR-Cas 9, TPF-Nanomission, DST, India; Collaborator: Dr Lekshmi Sumitra, ACNS
  • Translational Development of Protein-Sorafenib nanomedicine, Dept of Biotechnology (DBT)
  • Translational development of nCP nanotheranostic agent, Dept of Biotechnology (DBT)
  • Nano-Photomedicine for Glioblastoma, M/s Lead Invent Pharma, USA,
  • Indo-Singapore Grant on stem cell tracking using nCP:Fe contrast agent (DBT), with Prof. Kishore Bhakoo, SBIC, Singapore
  • Portable Cancer Raman Device (DBT) : Dept of Biotechnology (DBT) with Dr Girish C M
  • Gamma Delta T Cell cancer immunotherapy, as Co-PI with Dr Anusha, SERB-DST
  • Nanoengineered autoantigens for the prevention and treatment of autoimmunity, Indo-Australian project with Dr K Menon and Claud Bernard, Monash University:
  • Controlled release of human hormones, M/S Function Promoting Technologies (FPT), Cambridge, USA

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