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MRI and CT Contrast-enabled Composite Implants for Image-guided Tissue Regeneration and Therapy (Filed)

Publication Type : Patents

Thematic Areas : Nanosciences and Molecular Medicine

Publisher : Amrita Vishwa Vidyapeetham,

Source : Amrita Vishwa Vidyapeetham, Volume US Patent 10,806,805, India (2020)

Url : https://patentscope.wipo.int/search/en/detail.jsf?docId=US237648948&recNum=94&docAn=16081931&queryString=EN_TI:tissue%20engineering%20OR%20EN_AB:tissue%20engineering&maxRec=15106

Campus : Kochi

School : Center for Nanosciences

Center : Amrita Center for Nanosciences and Molecular Medicine Move, Nanosciences

Department : Nanosciences and Molecular Medicine

Year : 2017, 2020

Abstract : A composite implant for providing simultaneous magnetic resonance imaging (MRI) and computed tomographic (CT) imaging contrast is disclosed. The composite implant is formed of a calcium compound in the form of nano or microparticles doped with a first dopant configured to provide MRI contrast and a second dopant configured to provide CT contrast. The calcium compound is loaded onto a polymer gel matrix and lyophilized to form a mass with 3-dimensionally interconnected porosity, configured to provide tissue integration and proliferation sites. Methods of forming the composite implant are also disclosed. The implant could be a scaffold or bead structured to enable treatment of human or animal patient for bone/cartilage injury or defect by implantation, with MRI and CT monitoring.

Cite this Research Publication : Anusha Ashokan, Dr. Manzoor K., Shantikumar V Nair, M, S., and Harish, V., “MRI and CT Contrast-enabled Composite Implants for Image-guided Tissue Regeneration and Therapy (Filed)”, U.S. Patent PCT/US2017/0207932017.

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