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Publication Type : Patents
Thematic Areas : Nanosciences and Molecular Medicine
Publisher : Amrita Vishwa Vidyapeetham,
Source : Amrita Vishwa Vidyapeetham, Volume US Patent 10,806,805, India (2020)
Campus : Kochi
School : Center for Nanosciences
Center : Amrita Center for Nanosciences and Molecular Medicine Move, Nanosciences
Department : Nanosciences and Molecular Medicine
Year : 2017, 2020
Abstract : A composite implant for providing simultaneous magnetic resonance imaging (MRI) and computed tomographic (CT) imaging contrast is disclosed. The composite implant is formed of a calcium compound in the form of nano or microparticles doped with a first dopant configured to provide MRI contrast and a second dopant configured to provide CT contrast. The calcium compound is loaded onto a polymer gel matrix and lyophilized to form a mass with 3-dimensionally interconnected porosity, configured to provide tissue integration and proliferation sites. Methods of forming the composite implant are also disclosed. The implant could be a scaffold or bead structured to enable treatment of human or animal patient for bone/cartilage injury or defect by implantation, with MRI and CT monitoring.
Cite this Research Publication : Anusha Ashokan, Dr. Manzoor K., Shantikumar V Nair, M, S., and Harish, V., “MRI and CT Contrast-enabled Composite Implants for Image-guided Tissue Regeneration and Therapy (Filed)”, U.S. Patent PCT/US2017/0207932017.