Qualification: 
Ph.D, MSc
Email: 
s_giri@blr.amrita.edu

Dr. S. Giridhar Reddy currently serves as Assistant Professor at the department of Chemistry, Amrita School of Engineering, Bengaluru campus. His Ph.D. thesis is titled “Studies on the swelling properties of biodegradable sodium alginate and lignosulphonic acid blends for controlled drug delivery” at Amrita School of Engineering, Amrita Vishwa Vidyapeetham, Bengaluru Campus.He is working as Assistant Professor in ASE Bengaluru from past 13 years and also doing research in Polymers, Nanoscience, and Controlled drug delivery. 

Publications

Publication Type: Journal Article

Year of Conference Publication Type Title

2017

Journal Article

Dr. S. Giridhar Reddy and Dr. Amrita Thakur, “Biogenic Synthesis Of Silver Nanoparticles Using Plant Waste Material”, Rasayan Journal of Chemistry, vol. 10, no. 2, 2017.

2016

Journal Article

Dr. S. Giridhar Reddy, Dr. Akanksha Saxena Pandit, and Dr. Amrita Thakur, “Effects of crosslink agents on sodium alginate and lignosulphonic acid blends”, Polymer (Korea), vol. 40, pp. 63-69, 2016.[Abstract]


Blends of sodium alginate (SA) and lignosulphonic acid (LS) has been prepared in the ratio of 80/20. The prepared blends were crosslinked using chlorides of calcium, barium, strontium and aluminum. The crosslinking of blends was done for different time intervals and then these blends were subjected for swelling studies in aqueous medium of pH 7.4. The observations indicate that the crosslinking is diffusion controlled and is affected by the size of metal ion and the type of alginate used. The improved swelling time for crosslinked blends in aqueous medium supports the fact that the stability under physiological conditions of the blends is improved due to crosslinking with the metal ions. Calcium chloride and barium chloride forms strong crosslink with the blend. Calcium ion crosslinked blends can be considered suitable for biomedical drug applications. The investigations on crosslinked blends using FTIR, SEM, XRD and EDAX are in close agreement with swelling results. © 2016 The Polymer Society of Korea. All rights reserved.

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2016

Journal Article

Dr. Amrita Thakur and Dr. S. Giridhar Reddy, “Biological Materials: Green Source Towards Silver Nanomaterials Synthesis”, Oriental Journal of Chemistry, vol. 32, no. 3, pp. 1465-1472, 2016.[Abstract]


The synthesis of silver nanoparticles is of great importance because of the fact that their application is sensitive to the shape, size and its distribution. Bio medical application also demands that nanoparticles should be free from contaminants. Quest for synthetic methods which are benign to both human and environment led researchers to use locally available biogenic products for silver nanoparticle synthesis. Present review article, is based on the available literature on the use of microorganisms and plants for silver nanoparticle synthesis. Also the factors affecting the synthesis, role of phyto chemicals and proposed application of synthesized nanoparticles have been reported. More »»

2016

Journal Article

Dr. S. Giridhar Reddy and Dr. Akanksha Saxena Pandit, “Mass Transfer Characteristics of Sodium alginate (SA) and Lignosulphonic acid (LS) Blends”, An International Research Journal of Pure and Applied Chemistry, vol. 32, no. 5, 2016.[Abstract]


Diffusion and sorption of Biodegradable blends of sodium alginate (SA) and lignosulphonic acid (LS) has been studied at room temperature by conventional weight gain experiments. The sorption studies of SA/LS blends are carried in pH medium of 7.4. The sorption data are used to evaluate the mass transfer coefficients such as intrinsic diffusion coefficient and permeation coefficient. It was observed that the blends follow Fickian mode of transport where polymer chain relaxation is more than diffusion of solvent. More »»

2014

Journal Article

Dr. S. Giridhar Reddy and Dr. Akanksha Saxena Pandit, “Controlled drug delivery studies of biological macromolecules: Sodium alginate and lignosulphonic acid films”, Journal of Applied Polymer Science, vol. 131, 2014.[Abstract]


The ciprofloxacin (CPX)-loaded blends made of sodium alginate and lignosulfonic acid (LS) were prepared by solution casting method in the ratio of 80/20. The blends were crosslinked for different intervals of time to control the drug release. The drug release was investigated for 24 hours in different pH medium (1, 4, 7, and 9). It was confirmed that drug release is controlled by diffusion through the polymer matrix followed by the erosion of the polymer. The pH of the surrounding medium influences the drug solubility, swelling, and degradation rate of the polymer and therefore the overall drug release process. The blend shows minimal drug release at pH 1 and 9, whereas moderate release at pH 4, but rapid release at pH 7. Further FTIR, XRD, and SEM characterization are carried, to confirm the chemical-interaction, crystallization effects, and compatibility between the blend matrixes. Copyright © 2014 Wiley Periodicals, Inc. More »»

2013

Journal Article

Dr. S. Giridhar Reddy and Dr. Akanksha Saxena Pandit, “Effect of Curing Agent on Sodium Alginate Blends Using Barium Chloride as Crosslinking Agent and Study of Swelling, Thermal, and Morphological Properties”, International Journal of Polymeric Materials and Polymeric Biomaterials, vol. 62, pp. 743-748, 2013.[Abstract]


Sodium alginate and lignosulfonic acid blends were prepared in various ratios (100/0, 80/20, and 60/40), in order to test the suitability of these blends for controlled drug delivery in variable pH medium using barium chloride as crosslinking agent. The blends were characterized by TGA and DSC, in order to study thermal degradation properties and glass transition temperature. Thermal analyses of blends were found to be degrading in multiple steps compared to their pure polymers. Crystallization characteristics are investigated using the DSC curves. Further, miscibility of blends was investigated for morphological studies by SEM. More »»

2013

Journal Article

Dr. S. Giridhar Reddy and Dr. Akanksha Saxena Pandit, “Biodegradable sodium alginate and lignosulphonic acid blends: characterization and swelling studies”, Pol{ímeros, vol. 23, pp. 13–18, 2013.[Abstract]


In this article, Sodium alginate and Lignosulphonic acid blends were prepared in different weight ratios by solution casting method. Swelling experiments were conducted for Sodium alginate and its blends by adding calcium chloride for various intervals in a pH 7.4 medium. The strength of the films increases after their treatment with CaCl2 at higher intervals forming an alginate network. The SA/LS blend (80/20) is subjected for sorption studies at variable pH 1.2 & 7.4, in order to test the suitability of the blends for controlled drug delivery. Further, experiments were conducted for de-crosslinking using 0.1M HCl. The solvent uptake for the blends decreased with increasing LS content in the blends. Blends were investigated by X-ray diffraction and Fourier Transform Infra-Red spectroscopy in order to study the crystallinity and molecular interactions. XRD confirms the reduction in cluster space in blends leading to lower uptake of solvent.

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2011

Journal Article

Dr. S. Giridhar Reddy and Dr. Akanksha Saxena Pandit, “Swelling behavior of calcium-ions crosslinked bipolymeric sodium alginate-lignosulphonic acid blends”, International Journal of Polymeric Materials and Polymeric Biomaterials, vol. 60, pp. 1123-1129, 2011.[Abstract]


A series of blends based on lignosulfonic acid (LSA) and sodium alginate (NaAlg) were prepared with varying proportions of NaAlg and LSA using a solution-casting method. The swelling /degradation behavior of blends was studied so that they can be used for gastrointestinal drug delivery. Effect of crosslinking, pH, alginate content, and treatment with strong acid on swelling properties of the blends was investigated. It was found that blends show pH-sensitive swelling and show less water uptake due to crosslinking, while crosslinking is reduced in the presence of strong acid. Thus these blends offer their strong candidature for possible use in drug delivery. Copyright © Taylor & Francis Group, LLC. More »»

Publication Type: Conference Paper

Year of Conference Publication Type Title

2016

Conference Paper

Dr. Amrita Thakur and Dr. S. Giridhar Reddy, “Green Synthesis Of Silver Nanoparticles Using Sodium Alginate And Lignosulphonic Acid Blends”, in International Conference on Advanced Material Technologies (ICAMT), 2016.[Abstract]


A simple method based on the principles of green chemistry has been developed to synthesize stable silver nanoparticles (AgNP) for possible biomedical applications. Blend of sodium alginate (SA) and lignosulphonic acid (LS) prepared in the ratio of 80/20 mass percent respectively was used as reducing and stabilizing agent. This blend is biocompatible and has shown drug release ability under physiological conditions. Use of blend has an added advantage as LS has the ability to reduce silver while the blend matrix acts as a stabilizing agent. Effect of precursor concentration (AgNO3) and temperature was investigated. Progress of synthesis was monitored using UV-Vis spectroscopy. Higher temperature and lower silver nitrate concentration showed better synthesis of AgNP.

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2014

Conference Paper

Dr. S. Giridhar Reddy and Dr. Akanksha Saxena Pandit, “Compatibility and Control Release Studies of Sodium Alginate (SA)/ Lignosulphonic acid (LS) Blends using Ciprofloxacin as model drug”, in International conference on functional materials ICFM- 2014, 2014.

2013

Conference Paper

Dr. S. Giridhar Reddy and Dr. Akanksha Saxena Pandit, “DRUG DELIVERY STUDIES OF SODIUM ALGINATE AND LIGNOSULPHONIC ACID BLENDS”, in International conference on Polymers on the Frontiers of Science & Technology, Under the auspices of APA 2013 (Asian Polymer Association), 2013.

2010

Conference Paper

Dr. S. Giridhar Reddy and Dr. Akanksha Saxena Pandit, “Crystallization and Swelling of Novel Biodegradable polymer: Sodium alginate and Lignosulphonic acid”, in PROCEEDINGS OF POLYMER SCIENCE AND ENGINEERING: EMERGING DIMENSIONS (PSE-2010), Under the auspices of APA 2013 (Asian Polymer Association), 2010.

2010

Conference Paper

Dr. S. Giridhar Reddy and Dr. Akanksha Saxena Pandit, “SWELLING STUDIES ON BIODEGRADABLE POLYMERS”, in Second International Conference on Polymer Processing and Characterization (ICPPC – 2010), 2010.

Publication Type: Conference Proceedings

Year of Conference Publication Type Title

2015

Conference Proceedings

Dr. S. Giridhar Reddy and Dr. Amrita Thakur, “Greener Approach towards the Synthesis of Silver Nanoparticles by Biological Methods”, RAINSAT 2015. Sathyabama University, India, 2015.

2012

Conference Proceedings

Dr. S. Giridhar Reddy and Dr. Akanksha Saxena Pandit, “Thermal and Morphological characterization of Sodium Alginate and Lignosulphonic acid Blends”, IMPC 2012. M.G.University, Kottayam, Kerala, India, 2012.

2011

Conference Proceedings

Dr. S. Giridhar Reddy and Dr. Akanksha Saxena Pandit, “Effect of Sodium Alginate on SA/LS blends for pH-Responsive Swelling for Drug delivery to the Gastrointestinal Tract”, APSRT 2011. IIT Kharagpur, India., 2011.

2010

Conference Proceedings

Dr. S. Giridhar Reddy and Dr. Akanksha Saxena Pandit, “Swelling Behavior of Calcium–Ions Cross linked Bipolymeric Sodium Alginate–Lignosulphonic acid blends”, ICPPC 2010. M.G. University, Kerala, India, 2010.

2008

Conference Proceedings

Dr. S. Giridhar Reddy and , “Alginate –A futuristic Novel Biomaterial”. FPM 2008”, National Conference on Futuristic Polymer Materials. RVCE, Bangalore, 2008.

207
PROGRAMS
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AMRITA
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