Back close

A Rhodamine based Fluorescent Probe Validates Substrate and Cellular Hypoxia Specific NADH Expression

Publication Type : Journal Article

Thematic Areas : Advanced Materials and Green Technologies

Publisher : Chem Commun (Camb), Volume 55, Issue 4, p.537-540 (2019)

Source : Chem Commun (Camb), Volume 55, Issue 4, p.537-540 (2019)

Url : https://pubs.rsc.org/en/content/articlelanding/2019/cc/c8cc08991d#!divAbstract

Campus : Coimbatore

School : School of Engineering

Center : Center for Excellence in Advanced Materials and Green Technologies

Department : Civil

Abstract : Herein, we report a rhodamine-based redox probe (MQR) to visualize cytosolic NADH in the cellular milieu. Its high sensitivity and selectivity allowed it to track the alteration of the NADH level under metabolic perturbation, suggesting its potential as a useful tool to study the association between the NADH level and metabolic abnormalities with clinical significance.

Admissions Apply Now