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Cysteamine derived N/S co-doped carbon dots for fluorescence imaging of pathogenic bacteria and human buccal epithelial cells

Publication Type : Journal Article

Publisher : Elsevier

Source : Materials Letters, Volume 305, 2021, 130725, ISSN 0167-577X

Url : https://www.sciencedirect.com/science/article/abs/pii/S0167577X21014221

Campus : Coimbatore

Center : Biosensor Research Lab

Department : Sciences

Verified : Yes

Year : 2022

Abstract : Here, we report cysteamine derived nitrogen and sulfur co-doped carbon dots (Cy@CD) for imaging pathogenic bacteria and human buccal epithelial cells. The Cy@CD was synthesized using one-step simple microwave-assisted hydrothermal synthesis with precursors, namely, cysteamine and 50X TAE buffer. The spectroscopic characterization of Cy@CD showed (λex/λem) at 350/434 nm with a decent quantum yield of 13.2%. Cy@CD was deployed in tagging bacterial cells such as E. coli, S. aureus, P. aeruginosa and B. subtilis and human buccal epithelial cells. The multicolour emissive Cy@CD tagged microbial cells were also cross-validated by fluorometry analysis. The fluorescent Cy@CD could be used as an ideal substitute for the harmful synthetic fluorescent stain in cell imaging applications.

Cite this Research Publication : Abhishek Pathak, J.P. Chandhana, Aswin Ratheesh, Bipin G. Nair, Punathil Vasu Suneesh, T.G. Satheesh Babu,
Cysteamine derived N/S co-doped carbon dots for fluorescence imaging of pathogenic bacteria and human buccal epithelial cells, Materials Letters, Volume 305, 2021, 130725, ISSN 0167-577X,
https://doi.org/10.1016/j.matlet.2021.130725.

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