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Publication Type : Journal Article
Thematic Areas : Medical Sciences
Publisher : BMC Infectious Diseases,
Source : BMC Infectious Diseases, 2021.
Campus : Kochi
School : School of Medicine
Department : Microbiology
Year : 2021
Abstract : Background Candida auris infections are an emerging global threat with poor clinical outcome, high mortality rate, high transmission rate and outbreak potential. The objective of this work is to describe a multidisciplinary approach towards the investigation and containment of a Candida auris outbreak and the preventive measures adopted in a resource limited setting. Methods This outbreak investigational study was conducted at a 1300-bedded tertiary care academic hospital in South India. The study included 15 adult inpatients with laboratory confirmed Candida auris isolates. The outbreak cluster was identified in adult patients admitted from September 2017 to 2019. The system response consisted of a critical alert system for laboratory confirmed Candida auris infection and multidisciplinary ‘Candida auris care team’ for patient management. The team implemented stringent Infection Prevention and Control (IPC) measures including patient cohorting, standardized therapy and decolonization, staff training, prospective surveillance and introduction of Candida auris specific care bundle. Results Two outbreak clusters were identified; first cluster occurring between October and November 2017 and the second cluster in May 2018. The cohorts consisted of 7 and 8 Candida auris positive patients in the first and second waves of the outbreak respectively with a total survival rate of 93% (14/15). Deployment of containment measures led to gradual decline in the incidence of adult Candida auris positive cases and prevented further cluster formation.
Cite this Research Publication : Dipu Thareparambil Sathyapalan, Remya Antony, Vrinda Nampoothiri, Anil Kumar, Nandita Shashindran, Jini James, Jisha Thomas, Preetha Prasanna, Akkulath Sangita Sudhir, Jeslyn Mary Philip, Fabia Edathadathil, Binny Prabhu, Sanjeev Singh & Merlin Moni "Evaluating the measures taken to contain a Candida auris outbreak in a tertiary care hospital in South India: an outbreak investigational study", BMC Infectious Diseases, 2021.