Publication

Abstract : pOral route is one of the most preferred routes of drug administration because of low-cost and ease of administration increases the patient compliance. Many patients especially geriatric and paediatric have difficulty to swallow the tablets and hard gelatine capsules. Fast dissolving drug delivery systems (FDDDS) were developed as an alternative to tablet, capsule and syrups. Among this, fast dissolving oral thin-films are useful in patients such as paediatric, bedridden or developmentally disabled, geriatric, who face difficulty in swallowing tablets or hard gelatine capsules. Oral fast dissolving film is relatively a new dosage form in which thin film is prepared using hydrophilic polymers, which rapidly disintegrate or dissolves on tongue or in the buccal cavity. It is an alternative platform for molecules that undergoes high first pass metabolism. The present review gives an account of different formulations, methods of preparation and quality control of the fast dissolving oral thin films. © 2016, Global Research Online. All Rights Reserved./p