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First row transition metal complexes of bis(3,5-dimethyl pyrazolyl)methane: Synthesis, molecular structure and antibacterial properties

Publication Type : Journal Article

Publisher : Elsevier

Source : Journal of Molecular Structure, Volume 1251, Pages 132018 (2022)

Campus : Amritapuri

School : School of Engineering

Center : AmritaCREATE

Year : 2022

Abstract : A series of nine transition metal complexes was synthesized by reacting bis(3,5-dimethylpyrazolyl)methane (BP) with the respective metal chlorides in 1:1 and 2:1 stochiometric proportions. The complexes were duly characterized by molar conductivity measurement, IR, UV, NMR spectroscopy and elemental analysis. Using X-ray analysis, solid state molecular structures of the complexes C3 and C8 were determined. The molecular structures and the stoichiometry of the obtained complexes were found to be governed by the steric factors of the ligand substituents. The prepared compounds were found to be bactericidal against the four bacterial stains tested, however with high MIC/MBC values.

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