Publication

Abstract : The synthesis of AgNPs (silver nanoparticles) was performed using the aqueous extract of seagrass Halodule uninervis (HU) along with silver nitrate. The synthetic production of HU-AgNPs was confirmed by a color change and analyzed with a UV–vis spectrophotometer at 450 nm. The existence of functional groups was verified using Fourier transform infrared (FTIR) spectroscopy. The HU-AgNPs’ spherical shape was validated by scanning electron microscopy (SEM) tests. The crystal structure of HU-AgNPs was established by X-ray diffraction (XRD). The roughness and surface morphology were confirmed by atomic force microscopy (AFM). Significant antibacterial action was demonstrated by the HU-AgNPs against Pseudomonas aeruginosa and Escherichia coli, two Gram-negative pathogens. The antioxidant showed the highest inhibition of ABTs (2,2′-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid)) when compared to hydroxyl scavenging, 2,2′-diphenyl-2-picrylhydroxyl (DPPH), hydrogen peroxide (H2O2), nitric oxide (NO), and superoxide tests. By inhibiting α-amylase along with α-glycosidase, the HU-AgNPs’ antidiabetic effectiveness was evaluated. Therefore, to validate the findings and create an antibacterial, anti-inflammatory, antioxidant, and antidiabetic drug, a molecule-level in vivo study is required. Such synthesized nanoparticles have potential applications in multifunctional drug delivery applications.