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NiCl2·6H2O/NaBH4 in methanol: a mild and efficient strategy for chemoselective deallylation/debenzylation of aryl ethers

Publication Type : Journal Article

Publisher : Elsevier

Source : Tetrahedron Letters, 2013

Campus : Amritapuri

School : School of Biotechnology

Verified : No

Year : 2013

Abstract : Deprotection of allyl/benzyl aryl ethers was achieved chemoselectively. The mild and inexpensive reagent combination of NiCl2·6H2O/NaBH4 in methanol afforded the products in high yields, within a reaction time of 5–10 min.

Cite this Research Publication : Mangilal Chouhan, Kapil Kumar, Ratnesh Sharma, Vikas Grover and Vipin A. Nair, "NiCl2.6H2O/NaBH4 in methanol: a mild and efficient strategy for chemoselective
deallylation/debenzylation of aryl ethers", Tetrahedron Letters, 2013, 54, 4540-4543

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