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Publication Type : Journal Article
Thematic Areas : Center for Computational Engineering and Networking (CEN)
Publisher : Journal of Applied Pharmaceutical Science, Open Science Publishers LLP Inc
Source : Journal of Applied Pharmaceutical Science, Open Science Publishers LLP Inc., Volume 5, Issue 9, Number 9, p.097-099 (2015)
Campus : Amritapuri, Coimbatore
School : School of Biotechnology
Center : Computational Engineering and Networking
Department : Center for Computational Engineering and Networking (CEN)
Year : 2015
Abstract : The tuberculosis (TB) is a major infectious disease in the world, which is still not made under control. Mannose binding lectin (MBL) or MBL2 is a human gene susceptible to Tuberculosis and is used as a tool to investigate the proneness of attack by mycobacterium tuberculosis. MBL2 gene has been found over fifty five different populations in India. Among the identified single-nucleotide polymorphism (SNP) investigated in this work by evaluating the SNPs through computational methods. All identified SNPs are reported as deleterious. The SNP, rs1800450 of MBL2 is commonly reported from all major genomic populations in India, and the individuals holding this SNP are prone to the attack of mycobacterium tuberculosis. © 2015 C.V. Umesh et al.
Cite this Research Publication : C. V. Umesh, Jamsheer, A. M., Alex, P. M., and P. K. Krishnan Namboori, “Perusal of Mbl2 gene -Susceptibility to tuberculosis in different Indian populations”, Journal of Applied Pharmaceutical Science, vol. 5, no. 9, pp. 097-099, 2015.