Publication Type : Journal Article
Publisher : National Library of Medicine
Source : Neurol India. 2023 Jan-Feb;71(1):62-71. doi: 10.4103/0028-3886.370470. PMID: 36861576.
Url : https://pubmed.ncbi.nlm.nih.gov/36861576/
Campus : Kochi
School : School of Medicine
Year : 2023
Abstract : Between January 2017 and May 2022, 235 patients were screened and 138 histologically proven and radiologically confirmed. One to five brain metastasis patients aged more than 18 years with good Karnofsky performance status (KPS >70) accrued in ethical and scientific committee-approved prospective observational study protocol for treatment with only radiosurgery (SRS) with robotic radiosurgery (CyberKnife, CK) [AIMS IRB: 2020-071; CTRI No: REF/2022/01/050237]. Immobilization was performed with a thermoplastic mask, contrast CT simulation was performed with 0.625 mm slices, fused with T1 contrast/T2 FLAIR MRI images for contouring. Planning target volume (PTV) margin of 2-3 mm and a dose of 20-30 Gy in 1-5 fractions. Response to treatment, new brain lesions free survival, overall survival, and toxicity profile after CK were evaluated.
Cite this Research Publication : Dutta D, Reddy SK, Kamath RK, Sreenija Y, Nair H, Sashidharan A, Remesan Nair RA, Pushpuja KU, Kannan R, Edappattu A, Haridas NK, Jose WM, Keechilat P. "Prospective Evaluation of Response to Treatment, Survival Functions, Recurrence Pattern and Toxicity Profile in Indian Patients with Oligo-Brain Metastasis Treated with Only SRS". Neurol India. 2023 Jan-Feb;71(1):62-71. doi: 10.4103/0028-3886.370470. PMID: 36861576.