Publication Type : Journal Article
Publisher : SpectrochimicaActa Part A
Source : SpectrochimicaActa Part A, 2014, 118, 1152-1157
Url : https://pubmed.ncbi.nlm.nih.gov/24184586/
Campus : Mysuru
Department : Chemistry
Year : 2014
Abstract : In this paper, we describe the synthesis of novel class of pseudo-peptides derived by coupling an amino acid with a heterocyclic moiety containing free amine group using suitable coupling agents. The synthesized compounds were characterized using spectral ((1)H NMR, (13)C NMR and MS) techniques. Preliminary pharmacological assays for Leptospirosis were studied by test tube dilution (TDT) and micro dilution technique (MDT). In particular, all the analyses led to the conclusion that the synthesized compound inhibiting the Leptospira a causal organism of Leptospirosis.
Cite this Research Publication : K. Shiva Prasadet al.,“Pseudo-peptides as novel antileptospiral agents: Synthesis and spectral characterization” SpectrochimicaActa Part A, 2014, 118, 1152-1157. DOI:10.1016/j.saa.2013.09.105