Vesicular drug delivery system has overtaken the pre existing drugs by improving therapeutic efficacy and by sustaining and controlling action. Liposomes, herosomes, sphingosomes, ethosomes, cubosomes, pharmacasomes, niosomes, transferosomes are the newly developed vesicular drug delivery system. This article mainly deals with the sphingosomal drug delivery system. It provides a brief description about advantages and disadvantages of sphingosomes, the main classification of sphingosomes and highlights about its applications. Sphingosomes are vesicular drug delivery system which is made up of a lipid bilayer membrane enclosing an aqueous volume. Because of its wide variety of application in treatment of cancer, cosmetics, gene delivery, ocular drug delivery; it has become a better area of field of study. These systems have enhanced therapeutic index of all drugs by encapsulating these medications inside aqueous volume. © 2016, International Journal of Pharmaceutical Sciences Review and Research.
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K. M. Fathima, Nitheesh, A., Paul, A., and Sreeja C. Nair, “Sphingosome vescicular system”, International Journal of Pharmaceutical Sciences Review and Research, vol. 41, pp. 208-213, 2016.