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Synthesis of luminescent 2,3-diphenylmaleimide-labelled peptide nucleic acid oligomers

Publication Type : Journal Article

Publisher : Tetrahedron Letters

Source : Tetrahedron Letters Volume 59 Issue 23 Pages 2229-2231, 2018

Url : https://www.sciencedirect.com/science/article/abs/pii/S0040403918303745

Campus : Coimbatore

School : School of Physical Sciences

Year : 2018

Abstract : A lys-GTAGATCACT-lys peptide nucleic acid (PNA) decamer labelled with the luminescent 2,3-diphenyl maleimido (DPM) group on the ε-position of the terminal lysine residue was prepared through an automated solid phase synthesis. Fluorescence emission of the DPM-labelled PNA thus obtained was found to be significant and promising for the potential application in DNA recognition. © 2018

Cite this Research Publication : Prasanna Ramani, Silvia Cauteruccio, Emanuela Licandro, Clara Baldoli, "Synthesis of luminescent 2, 3-diphenylmaleimide-labelled peptide nucleic acid oligomers", Tetrahedron Letters Volume 59 Issue 23 Pages 2229-2231, 2018

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