Publication Type : Journal Article
Thematic Areas : Medical Sciences
Publisher : Cancer Letters
Source : Cancer Letters, Volume 81, Number 2, p.171-175 (1994)
Keywords : 2 (3 aminopropylamino)ethanethiol, animal, animal experiment, animal model, antineoplastic agent, article, cancer chemotherapy, controlled study, DNA damage, doxorubicin, drug toxicity, ehrlich ascites tumor, free radical, heart injury, Inbred BALB C, lipid peroxidation, liver injury, Lung injury, Mercaptoethylamines, Mice, mouse, nonhuman, priority journal, protective agent
Campus : Kochi
School : School of Medicine
Year : 1994
Abstract : The protective effect of WR-1065 against the side effects of Adriamycin was studied in tumor bearing mice. It has been noticed that WR-1065 pretreatment improved the Adriamycin toxicities such as increased enzyme levels, pathological lesions in lung, liver and heart and increased rate of lipid peroxidation, without reducing its anticancer property.
Cite this Research Publication : Dr. Damodaran Vasudevan, Bhanumathi, P., and Saleesh, E. D., “WR-1065 as a chemoprotector in Adriamycin chemotherapy”, Cancer Letters, vol. 81, pp. 171-175, 1994.