Course

The Development and Causes of Cancer, Tumor Viruses, Oncogenes, Tumor Suppressor genes, Cell cycle and its control, Apoptosis, Telomeres, cellular immortalization and tumorigenesis, Cancer Stem Cells, Angiogenesis and Metastasis, Cancer Epigenetics, Molecular Approaches to Cancer Treatment, Prevention, assessing risk, diagnostics and treatment

LEARNING OBJECTIVES:

This course covers in details the molecular mechanism of cancer development with emphasis on tumor viruses, oncogenes, tumor suppressor genes, cell cycle and its control and other hallmarks of cancer. It also covers the molecular approaches to cancer diagnostics and treatment. More recent advances in cancer stem cells and cancer epigenetics are also discussed

COURSE OUTCOMES:

After the successful completion of the course, the students shall be able to

CO1: Describe the different hallmarks of cancer,

CO2: Explain the role of oncogenes and tumor suppressors during the development of cancer

CO3: Understand the dysregulation of apoptosis and cell cycle in cancer

CO4: Identify the factors regulating angiogenesis and metastasis

CO5: Compare molecular approaches to cancer diagnostics and treatment.

CO6: Interpret data published in scientific journal articles and present cancer biology articles from reputed journals

REFERENCES:

1. The Biology of Cancer, 2^nd Edition, Robert A. Weinberg
2. Molecular Biology of the Cell. Alberts B. et al., (2008) 5thedition. Garland Science.
3. The Cell: A Molecular Approach, 4^th Edition, Geoffrey M. Cooper and Robert E. Hausman
4. Journal papers: reviews and research articles