Syllabus
Theory
Pre and post Mendelian concepts of heredity, Mendelian principles of heredity, Study of model organisms (Drosophila, Arabidopsis, Garden pea, E. coli, and mice), Architecture of chromosomes, chromonemata, chromosome matrix, chromomeres, centromere, secondary constriction and telomere, special types of chromosomes, Chromosomal theory of inheritance- cell cycle and cell division-mitosis and meiosis. Probabilit and Chi-square. Types of DNA and RNA, Dominance relationships, Epistatic interactions with example, Introduction and definition of cytology, genetics and cytogenetics and their interrelation. Multiple alleles, pleiotropism and pseudoalleles, Sex determination and sex linkage, sex limited and sex influenced traits, Blood group genetics, Linkage and its estimation, crossing over mechanism, chromosome mapping, Structural and numerical variations in chromosomes and their implications, Use of haploids, dihaploids and double haploids in Genetics, Mutation, classification, Methods of inducing mutations, mutagenic agents and induction of mutation. Qualitative and quantitative traits, Polygenes and continuous variations, multiple factor hypothesis, Cytoplasmic inheritance, Nature, structure and replication of genetic material, Protein synthesis, Transcription and translational mechanism of genetic material, Gene concept: Gene structure, function and regulation.
Practical
Study of microscope, Study of cell structure, Mitosis and Meiosis cell division, Experiments on monohybrid, dihybrid, trihybrid, test cross and back cross, Experiments on epistatic interactions including test cross and back cross, Practice on mitotic and meiotic cell division, Experiments on probability and chi-square test, Determination of linkage and cross-over analysis (through two point test cross data), Study on sex linked inheritance in Drosophila. Study on models on DNA and RNA structures.