| Course Name | Biomaterials Science |
| Course Code | 15CHY232 |
| Program | B. Tech. in Electrical and Electronics Engineering, B. Tech. in Civil Engineering, B. Tech. in Aerospace Engineering, B. Tech. in Chemical Engineering, B. Tech. in Mechanical Engineering, B. Tech. in Computer Science and Engineering |
| Year Taught | 2019 |
Introduction: Bulk properties, Surface properties and characterization – polymers, silicone biomaterials, medical fibres and biotextiles – Smart polymers – bioresorbable and bioerodible materials – natural materials, metals and ceramics – physicochemical surface modification.
Biocompatibility concepts: Introduction to biocompatibility – cell material interaction – types of materials – toxic, inert, bioactive – long term effects of materials within the body – cell response.
Chemical and biochemical degradation of polymers – degradation of metals and ceramics – calcification of biomaterials.
Host reactions and their evaluation: Inflammation and foreign body response – adaptive immunity – systemic toxicity and hypersensitivity – blood coagulation and blood materials interactions – device related infections.
Biological testing of biomaterials: Invitro and invivo assessment of tissue compatibility – evaluation of blood materials interaction – microscopy in biomaterials.
Practical aspects of biomaterials: Bioelectrodes, biomedical sensors and biosensors – sterilization of implants – implant failure – implant retrieval and evaluation – legal aspects, ethical issues and regulation aspects.
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