COURSE SUMMARY
Course Title: 
Introductory Biophysics
Course Code: 
BIO212
Semester: 
4
Degree: 
Undergraduate (UG)
School: 
School of Biotechnology
Campus: 
Amritapuri

'Introductory Biophysics' is a course offered for the BSc. Biotechnology at School of Biotechnology, Amrita Vishwa Vidyapeetham.

Thermodynamics of living systems: Conservation of energy in living systems, Entropy and Life, Gibbs and Standard free energy, Equilibrium constant, Coupled reactions.

Protein folding: Forces for protein stability, Protein denaturation and renaturation, Protein folding pathways, Levinthal’s paradox, Molten globule, Folding accessory proteins, Prediction of protein structures- Chou and Fasman method to predict secondary structures, Prediction of reverse turns.

Protein Function: Structure of heme, Structure of Myoglobin and hemoglobin, Oxygen binding mechanism, Oxygen binding co-operativity, Hill equation, Hill coefficient, Allostery in hemoglobin and structural changes, Bohr effect.

Dynamics of biomolecules: Diffusion, Fick's Laws of diffusion, Active transport, Facilitated diffusion, Diffusional flow across biological membranes, Osmosis, Osmotic pressure, Osmoregulation, Viscosity and biological importance- Factors affecting viscosity, Arterial blood flow, Synovial Fluid, Surface tension, Factors influencing surface tension, Biological importance- Function of Alveoli.