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A facile approach to substituted acrylates by regioselective and stereoselective addition of thiols and amines to an alkynyl ester in water

Publication Type : Journal Article

Publisher : Springer

Source : Monatshefte für Chemie, 2010

Url : https://link.springer.com/article/10.1007/s00706-010-0399-9

Campus : Amritapuri

School : School of Biotechnology

Verified : No

Year : 2010

Abstract : Water-promoted hydrothiolation and hydroamination of ethyl propiolate leading to highly regioselective and stereoselective formation of thioacrylates and β-enamino esters in excellent yields, by a simple, efficient, and environmentally friendly reaction procedure without employing any hazardous reagent or solvent is reported. Graphical Abstract

Cite this Research Publication : Nitin A. Randive, Varun Kumar and Vipin A. Nair, "A facile approach to substituted acrylates by regioselective and stereoselective addition of thiols and amines to an alkynyl ester in water", Monatshefte für Chemie, 2010, 141, 1329-1332

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