Publication Type : Journal Article
Publisher : IOP Publishing
Source : IOP Conference Series: Materials Science and Engineering, IOP Publishing, Volume 872, p.012125 (2020)
Url : https://doi.org/10.1088%2F1757-899x%2F872%2F1%2F012125
Campus : Amritapuri
School : School of Engineering
Center : Research & Projects
Department : Chemistry
Verified : Yes
Year : 2020
Abstract : Herein, a novel polymer film modified pencil graphite electrode as an electrochemical sensor for the propranolol hydrochloride (PROP) is reported. A poly nicotinamide modified pencil graphite (Poly-NA-PGE) electrode was used for the electrochemical detection of propranolol hydrochloride using differential pulse voltammetry. The modified electrode was characterized by Scanning Electron Microscopy. Furthermore, the experimental parameters like pH of the supporting electrolyte, concentration of the nicotinamide and polymerisation cycles were optimized. The cyclic voltammetry of propranolol hydrochloride showcased an irreversible oxidation peak at 0.9361V. The sensor showed a linear range from 1μM - 20μM with a correlation co-efficient of 0.99825. The repeatability of the electrode was excellent with an RSD of 3.5%. The sensor was utilized effectually for the determination of propranolol from the commercially available pharmaceutical tablet.
Cite this Research Publication : A Santhy, Dr. Beena S., Namboothiri, U. S. Krishnan, Anupriya, S., and Sreeranjini, C. V., “A pencil graphite electrode modified with poly nicotinamide as a framework for the electrochemical detection of propranolol hydrochloride”, IOP Conference Series: Materials Science and Engineering, vol. 872, p. 012125, 2020.