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Biosurfactants for pharmacological interventions in cancer therapy

Publication Type : Book Chapter

Publisher : Academic Press

Source : Academic Press (Elsevier), 2022, Chapter 22, Pages 421-437, ISBN: 9780323851466.

Url : https://www.sciencedirect.com/science/article/pii/B9780323851466000061

Campus : Kochi

School : School of Biotechnology

Department : biotechnology

Year : 2022

Abstract : The surface-active compounds produced by various microorganisms are termed as biosurfactants. These compounds are amphiphilic in nature and come under the class of glycoproteins, lipopeptides, or glycolipids. Biosurfactants are known to exhibit diverse biological functions such as antimicrobial, antifungal, antiviral, antiinflammatory, and anticancer activities. The role of biosurfactants in regulating various cancer progressions has gained more attention, recently. The anticancer potential is credited to the amphiphilic nature of biosurfactants, and various studies have shown that treatment of cancer cells with biosurfactants inhibits growth, arrests cell division, induces apoptosis, and prevents metastasis. This chapter aims to discuss about types and sources of biosurfactants and their anticancer potential against various cancers.

Cite this Research Publication : K.B. Arun, Shibitha Emmanual, Priya Krishna, Aravind Madhavan, Parameswaran Binod, Ashok Pandey and Raveendran Sindhu. Biosurfactants for pharmacological interventions in cancer therapy. In: Editors: Inamuddin, Charles Oluwaseun Adetunji and Mohd Imran Ahamed. Green Sustainable Process for Chemical and Environmental Engineering and Science Biomedical Application of Biosurfactant in Medical Sector. Academic Press (Elsevier), 2022, Chapter 22, Pages 421-437, ISBN: 9780323851466. DOI: https://doi.org/10.1016/B978-0-323-85146-6.00006-1.

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