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Chitosan-Based Nanoparticles in Cancer Therapy

Publication Type : Journal Article

Thematic Areas : Nanosciences and Molecular Medicine

Publisher : Advances in Polymer Science

Source : Advances in Polymer Science, Volume 243, Number 1, p.55-92 (2011)

Url :

ISBN : 9783642231131

Campus : Kochi

School : Center for Nanosciences

Center : Amrita Center for Nanosciences and Molecular Medicine Move, Nanosciences

Department : Nanosciences and Molecular Medicine

Year : 2011

Abstract : In recent years, many nanotechnology platforms in the area of medical biology, including cancer therapy, have attracted remarkable attention. In particular, research in targeted, polymeric nanoparticles for cancer therapy has increased dramatically in the past 5-10 years. However, the potential success of nanoparticles in the clinic relies on consideration of important parameters such as nanoparticle fabrication strategies, their physical properties, drug loading efficiencies, drug release potential, and, most importantly, minimum toxicity of the carrier itself. Recent work has suggested that chitosan materials hold much promise in advancing nanoparticle-based therapeutics. The field of oncology could soon be revolutionized by novel strategies for therapy employing chitosan-based nanotherapeutics. Several aspects of cancer therapy would be involved. Chitosans can also be applied to a variety of cancer therapies to improve their safety and efficacy. Further applications of chitosans in cancer therapy are being examined. This review focuses on providing brief updates on chitosan nanoparticles for cancer therapy. © 2011 Springer-Verlag Berlin Heidelberg.

Cite this Research Publication : V. - K. Lakshmanan, Bumgardner, J. D., Nair, S. V., Dr. Jayakumar Rangasamy, ,, and M., P., “Chitosan-Based Nanoparticles in Cancer Therapy”, Advances in Polymer Science, vol. 243, pp. 55-92, 2011.

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