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Publication Type : Journal Article
Thematic Areas : Nanosciences and Molecular Medicine
Publisher : Journal of Chitin and Chitosan Science
Source : Journal of Chitin and Chitosan Science, American Scientific Publishers, Volume 1, Number 1, p.13–20 (2013)
Campus : Kochi
School : Center for Nanosciences, School of Pharmacy
Center : Amrita Center for Nanosciences and Molecular Medicine Move, Nanosciences
Department : Nanosciences and Molecular Medicine, Pharmacy Practice
Verified : Yes
Year : 2013
Abstract : Coleus plectranthus, an herbal extract is an excellent wound healing agent for both acute and chronic wounds. Its anti-inflammatory property would be helpful to prevent scar formation. In this work, we developed coleus plectranthus herb extract incorporated chitosan sponge for wound healing applications. The morphology analysis of the prepared sponges was done by SEM analysis. The herb incorporated chitosan sponge showed high swelling ability in comparison to the conventional sponge. The protein adsorption ability of the prepared sponge was evaluated and the data proved the enhanced protein adsorption capability of the sponges. The sponges showed excellent antibacterial activity against Staphylococcus aureus, Klebsiella sp. and Acinetobacter sp. The cytocompatibility of the herb incorporated sponge was studied by cell cycle analysis and cell viability assay. These results showed that the sponges were cytocompatible and promote cellular growth.
Cite this Research Publication : L. R. Lakshman, Kumar, P. T., Nair, S. V., Nair, S. V., and Jayakumar, R., “Chitosan sponge containing the herb coleus plectranthus as a wound dressing”, Journal of Chitin and Chitosan Science, vol. 1, pp. 13–20, 2013.