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Effect of obesity on the toxicity profile of patients with breast cancer treated with adjuvant chemotherapy.

Publication Type : Conference Proceedings

Publisher : Journal of Clinical Oncology

Source : ASCO 2017. J Clin Oncol 35, 2017 (suppl; abstr e12033)

Url : https://ascopubs.org/doi/abs/10.1200/JCO.2017.35.15_suppl.e12033

Campus : Kochi

School : School of Medicine

Year : 2017

Abstract : Background: There is increasing evidence that obesity is strongly associated with breast cancer (BC) and has a major impact on the patient tolerance, overall survival (OS) and progression free survival (PFS). Chemotherapy dosing as per body surface area (BSA) or the actual body weight is a major dilemma among the oncologists. Moreover, the side effects of chemotherapy in obese patients in an Indian population has not been described previously in literature. We intended to evaluate the major toxicity, OS and PFS in obese BC patients who received adjuvant chemotherapy (ADC) with Adriamycin/cyclophosphamide (AC) and paclitaxel (T).

Cite this Research Publication : Srinivasalu V K, George AS, Philip A, Kotne S, Bhambroo S, Vijaykumar DK, Pillai R, Beena K, Jose W, Pavithran K (2017) Effect of obesity on the toxicity profile of patients with breast cancer treated with adjuvant chemotherapy. In: ASCO 2017. J Clin Oncol 35, 2017 (suppl; abstr e12033)

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