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Effect of silymarin in diabetes mellitus patients with liver diseases

Publication Type : Journal Article

Publisher : Journal of pharmacology & pharmacotherapeutics

Source : Journal of pharmacology & pharmacotherapeutics, Volume 2, p.287-9 (2011)

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Campus : Kochi

School : School of Pharmacy

Department : Pharmacy Practice

Year : 2011

Abstract : Previous studies have reported that silymarin reduces hepatic fibrosis via TGF-b1 and is associated with inhibiting glycogenolysis and gluconeogenesis through inactivation of the intrahepatic NF-kB signaling pathway (Jose et al., 2011). In the present study, we found that silymarin downregulated blood glucose level and significantly improved cardiac dysfunction in STZ-induced diabetic rats.

Cite this Research Publication : M. Jose, Abraham, A., and Dr. M.P.Narmadha, “Effect of silymarin in diabetes mellitus patients with liver diseases”, Journal of pharmacology & pharmacotherapeutics, vol. 2, pp. 287-9, 2011.

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