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Effect of Ursodeoxycholic Acid On Ethanol Induced Oxidative Stress In Liver

Publication Type : Journal Article

Thematic Areas : Medical Sciences

Publisher : SFRR Inida Bulletin

Source : SFRR Inida Bulletin, Volume 4, Number 2, p.15-19 (2006)

Campus : Kochi

School : School of Medicine

Year : 2006

Abstract : Alcohol consumption has been associated with alcoholic hepatitis, fatty infiltrataion of liver, accelerated progression of liver disease, a higher frequence of cirrhosis, with significant incidents of hepatocellular carcinoma, and death. There is no approved therapeutics intervention for alcoholic liver disease; hwever early stages are treatable. Ursodeoxycholic acid(ursidol) is a non-toxic cholestatic liver disorders.In the present study efficiacy of ursodiol to treat ethanol induced oxidatitive stress was monitored. It was found that ethanol-induced oxidative stess could be marginally prevented by ursodeoxycholic acid supplementation. Absentation from alcohol improved hepatic regeneration.

Cite this Research Publication : S. Kumar Das and Dr. Damodaran Vasudevan, “Effect of Ursodeoxycholic Acid On Ethanol Induced Oxidative Stress In Liver”, SFRR Inida Bulletin, vol. 4, pp. 15-19, 2006.

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