ProgramsView all programs
From the news
- Chancellor Amma Addresses the Parliament of World’s Religions
- Amrita Students Qualify for the European Mars Rover Challenge
Publication Type : Journal Article
Thematic Areas : Medical Sciences
Publisher : Indian Journal of Clinical Biochemistry
Source : Indian Journal of Clinical Biochemistry (2014)
Campus : Kochi
School : School of Medicine
Department : Biochemistry, Obstetrics & Gynaecology, Biostatistics
Year : 2014
Abstract : PCOS is a heterogeneous endocrine disorder with diverse clinical presentation. Oxidative stress plays a key role in the pathophysiology of this disease. Serumhigh sensitive C-reactive protein (hsCRP), a marker of chronic low grade inflammation, is indicative of future development of cardiovascular disease. Our aim is to evaluate the oxidant status and hsCRP levels in PCOS. The study involved 61 cases and 61 controls in the age group of 18-40 years diagnosed with PCOS. Erythrocyte malondialdehyde (MDA), superoxide dismutase (SOD), serum hsCRP, gonadotrophins, thyroid stimulating hormone, prolactin, glycemic status and lipid profile were estimated. Erythrocyte MDA (p lt; 0.001), SOD (p = 0.007) and serum hsCRP (p lt; 0.001) were significantly elevated in PCOS patients than controls. Oxidative stress is present in women with PCOS along with elevated hsCRP. © 2014 Association of Clinical Biochemists of India.
Cite this Research Publication : N. U. C. Sumithra, Lakshmi, R. L., N. Menon, L., Subhakumari, K. N., and Sheejamol V. S., “Evaluation of Oxidative Stress and hsCRP in Polycystic Ovarian Syndrome in a Tertiary Care Hospital”, Indian Journal of Clinical Biochemistry, 2014.