Publication Type : Journal Article
Source : Current Drug Therapy. 2021 Oct 1;16(5):448-53.
Url : http://www.eurekaselect.com/article/118163
Keywords : Fixed drug eruption, fixed drug combination, fluoroquinolones, nitroimidazoles, cross sensitivity, spontaneous desensitization.
Campus : Kochi
School : School of Pharmacy
Department : Pharmacy Practice
Verified : No
Year : 2021
Abstract : Fixed drug eruption (FDE) is an erythematous cutaneous patch caused by certain drugs through activation of immunologic reactions in the body. The onset of FDE is 30 minutes to 8 hours and is estimated to occur in upto 16-21% of all cutaneous reactions. The irrational combination of fluoroquinolones and nitroimidazole is the most prescribed drug for diarrhea in India, and the drug is found to cause FDE either individually or in combination. Cross sensitivity is the major issue associated with Fluoroquinolones and nitroimidazole.
Cite this Research Publication : Chaudhary RK, Metgudmath AR, Bhandari R, Karoli SS, R Uday Kumar R. Fixed drug eruptions secondary to fixed drug combination (ofloxacin/ornidazole):cross-sensitivityity case report. Current Drug Therapy. 2021 Oct 1;16(5):448-53.