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Potential application of dot immunobinding assay as a rapid diagnostic test in tuberculous meningitis

Publication Type : Journal Article

Source : Indian J Exp Biol 1991

Campus : Kochi

School : School of Medicine

Year : 1991

Abstract : A simple dot-immunobinding assay (Dot-Iba) in nitrocellulose paper was developed for the detection of specific IgG antibody to Mycobacterium tuberculosis antigen 5 and mycobacterial antigen in cerebrospinal fluid of patients with tuberculous meningitis (TBM). The assay gave 77.1% sensitivity for the detection of IgG antibody to M. tuberculosis antigen 5 and 48.6% sensitivity for the detection of mycobacterial antigen in patients with TBM.

Cite this Research Publication : Radhakrishnan V.V, Annamma M. Potential application of dot immunobinding assay as a rapid diagnostic test in tuberculous meningitis. Indian J Exp Biol 1991;29:437-440.

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