Publication Type : Journal Article
Publisher : Ovid Technologies (Wolters Kluwer Health)
Source : Annals of African Medicine
Url : https://doi.org/10.4103/aam.aam_851_25
Campus : Amritapuri
School : School of Ayurveda
Department : Rasashastra and Bhaishajya Kalpana
Year : 2026
Abstract :
The recently published case report on drug‑induced liver injury (DILI) attributed to traditional herbal medication provides an important reminder of the risks associated with prolonged, unsupervised intake of herbomineral formulations.[1] The article describes a 58‑year‑old woman who developed cholestatic hepatitis after consuming an Ayurvedic proprietary formulation, Mahayogaraja Guggulu, for joint pain approximately 3 months before symptom onset. The diagnosis of DILI was supported by a Roussel Uclaf Causality Assessment Method score of 7, and liver biopsy demonstrated focal hepatocellular necrosis, eosinophilic infiltration, and microvesicular steatosis
Cite this Research Publication : E. N. Prajeesh Nath, Devisree Damodaran, Revisiting Safety Determinants in the Use of Mahāyogarāja Guggulu: Role of Duration and Adjuvants, Annals of African Medicine, Ovid Technologies (Wolters Kluwer Health), 2026, https://doi.org/10.4103/aam.aam_851_25