Publication

Abstract : Orthotopic liver transplantation (OLT) has become one of the major routine operation and lifesaving procedure for many end-stage hepatic diseases like acute liver failure, hepatoma, Wilson’s disease, severe hepatitis, and decompensated liver diseases. The primary reason for morbidity and mortality after OLT is infections. Bacterial infections are the foremost common risk factor for morbidity in liver transplant recipients whereas viral and fungal infections also contribute. Liver transplant recipients with MELD score ≥ 30 are a specific subgroup of patients with an individual high- risk profile and they need close monitoring. The other risk factors include immunosuppression before transplantation, underlying condition of the recipient, co-morbidity associated with liver disorder i.e. diabetes, COPD, obesity, renal failure and dialysis, Acute liver failure, prolonged hospital stay and catheters before liver transplantation, ascites Spontaneous bacterial peritonitis before transplantation. Therefore, a better understanding of these risk factors should be considered and need attention to reduce this risk.