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Mass spectrometry based proteomic characterization of carbonylated proteins as indicators of oxidative stress
Mass spectrometry based proteomic characterization of carbonylated proteins as indicators of oxidative stress

Oxidative stress refers to the physiological stress caused by an imbalance between the systemic production of reactive oxygen species and the biological system’s ability to detoxify the reactive intermediates. It. . .

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Regulation of Inflammation by Natural Product extracts: Role in osteoclastogenesis
Regulation of Inflammation by Natural Product extracts: Role in osteoclastogenesis

Inflammation is the body’s endeavor at self-defense, the intent being to eradicate harmful stimuli, including damaged cells, irritants, or pathogens and begin the healing process.  It is one of the. . .

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Isolation and Characterization of Primary Tumor Cells
Isolation and Characterization of Primary Tumor Cells

 The lack of effective “in vitro” models to predict success of pharmacological therapy for patients with variety of cancer cell types demands the development of better experimental models to understand. . .

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Synthesis of Modified Benzophenanthridine – a Preliminary Anti-Cancer Study
Synthesis of Modified Benzophenanthridine – a Preliminary Anti-Cancer Study

Benzophenanthridines, naturally occurring isoquinoline alkaloids with various biological activities, are known to exist in five plant families, namely, the Fumariaceae (Genera Corydalis, Dicentra and Fumaria), the Papaveraceae, and the Rutaceae.. . .

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Mass Spectrometric Characterization of Bioactive Peptides and Proteins
Mass Spectrometric Characterization of Bioactive Peptides and Proteins

Plant diseases caused by bacteria and fungi are the major reasons for significant loss in crop yields. To address this issue, many strategies have been developed and new bioanalytical tools. . .

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Paraptosis: a Newer Approach to Target Cancer
Paraptosis: a Newer Approach to Target Cancer

The focus of the project is to screen molecules with anti-cancer properties and understand their mode of action with respect to cell death. Many cancer cells are apoptosis resistant; we. . .

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Peptide-Based Anti-Snake Venom Therapy
Peptide-Based Anti-Snake Venom Therapy

Typically, a snake bite is treated with polyclonal antibody preparations obtained from immunized animals. This method is suboptimal because the neutralizing agents are not tailored towards specific venom components and. . .

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Design and Validation of Point of Care Disposable Sensor Strips for Diagnosis of Tuberculosis from Urine Samples
Design and Validation of Point of Care Disposable Sensor Strips for Diagnosis of Tuberculosis from Urine Samples

Tuberculosis (TB) is believed to affect nearly one third of the world population with approximately 9 million new cases detected every year. Current methods of diagnosis includes sputum smear microscopy,. . .

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Affordable paper based microfluidics point of care testing device for liver function
Affordable paper based microfluidics point of care testing device for liver function

It is seen that therapies for diabetes and heart disease affects liver and these diseases are increasing in prevalence especially in developing countries. The liver metabolises and detoxifies drugs and. . .

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