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Supported Cell Mimetic Monolayers and their Blood Compatibility

Publication Type : Book Chapter

Publisher : Wiley Online Library

Source : Advanced Biomaterials: Fundamentals, Processing, and Applications, Edited by Bikramjit Basu Dhirendra S. Katti Ashok Kumar , Wiley Online Library, 2009, pp. 663–676

Url : https://onlinelibrary.wiley.com/doi/abs/10.1002/9780470891315.ch20

Keywords : biomimetic approaches in surface modification ‐ post‐synthetic modification of nanodevices, platelet adhesion and activation studies ‐ regulating formation of thrombus and medical device rejection, supported cell mimetic monolayers ‐ blood compatibility

Campus : Kochi

School : Center for Nanosciences, School of Pharmacy

Center : Amrita Center for Nanosciences and Molecular Medicine Move, Amrita Institute of Medical Science

Department : Nanosciences and Molecular Medicine, Pharmaceutics

Verified : Yes

Year : 2009

Abstract : The study of surface modification by using supported monolayers of phosphorylchlorine containing phospholipids for developing blood contracting materials were discussed. The study also focuses on blood compatibility of the supported monolayers of phospholipid , glycolipid and cholesterol binary and ternary lipid combinations using vitro techniques. The blood compatibility of these supported monolayers was studied by protein adsorption, blood cell adhesion and calcification. It was observed that an increase in calcification to the surface modified with loosely packed polar headgroup were helpful for the modification for blood-contacting materials.

Cite this Research Publication : Dr. Kaladhar Kamalasanan and Sharma, C. P., “Supported Cell Mimetic Monolayers and their Blood Compatibility”, in Advanced Biomaterials: Fundamentals, Processing, and Applications, Edited by Bikramjit Basu Dhirendra S. Katti Ashok Kumar , Wiley Online Library, 2009, pp. 663–676

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